Understanding the Link between Smell and PD
An opportunity to play a role in PD research
Early detection is a crucial step to understanding the causes of and developing better treatments for Parkinson’s disease (PD). Even before the typical tremor and slowness of movements occur in PD, it may be possible to detect early changes in the brain and symptoms that are associated with PD. For example, loss of sense of smell is a common but little noticed symptom that may occur years before the onset of motor symptoms or a PD diagnosis.
The Parkinson’s Progression Markers Initiative (PPMI) is a landmark clinical study to identify and assess biomarkers in people who are at risk to develop PD as well as those with typical PD symptoms. Ultimately, this strategy may enable researchers to develop better treatments for patients at an early stage of the disease that could, in turn, potentially delay or even prevent the onset of motor symptoms. Smell is a key risk factor being evaluated in PPMI.
View a letter from Michael J. Fox about the importance of this study.
Who is Needed?People over 60 who do not have Parkinson’s are needed for this study. Get started by taking our smell survey at www.michaeljfox.org/takethesmellsurvey.
Learn more about PPMI and the connection between smell loss and Parkinson’s disease by calling (877) 525-PPMI or downloading the smell brochure.
Take the Survey
Help Spread the Word
If you have Parkinson’s disease, you can play an important role. Invite your family and friends to participate by taking our survey. Refer a Friend
Purpose of the ResearchWhile most people with reduced sense of smell will not develop Parkinson’s disease, the majority of PD patients experience some smell loss. A reduced sense of smell in Parkinson’s disease patients most often begins several years prior to the onset of motor symptoms such as tremor, stiffness or slowness in movement and usually goes unnoticed until it is tested. Studying the sense of smell may therefore lead researchers to identify people at risk for Parkinson’s before the onset of motor symptoms.
Find out more about PPMI and reduced sense of smell at the Southeastern Parkinson Disease Conference, August 9 - 11, 2013 in Atlanta. To find out more about the Southeastern Parkinson Disease Conference